Grey’s Anatomy

Content Warning : This clause contains discourse of death

Although Meredith and Derek are known to be the fans ' preferent OTP , that did n’t mean there are n’t others that come a close second . One ofGrey ’s Anatomy’smost tragic love stories was between Mark and Lexie .

Mark and Lexie had a rollercoaster of a romance , have more ups and downs than any other couple . Despite break up more times than you could bet , the pair still managed to find their way back to one another . Unfortunately , their last reconciliation ended in catastrophe as both doctors died after buckle under to their injuries . In tribute to the union , here are five moments that proved they were twosome goals ( and five that proved they were n’t ) .

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update on May 12th , 2021 by Kayleigh Banks : With season 18 now formally support , fans are all wonder what other originative boulevard the writers will go explore ( specially as season 17 has been full of emotional surprise ) . Not only have Derek , George , and April made abbreviated coming into court , but Mark and Lexie also did too , providing lover with the closure they so desperately require . Everyone just hopes this impulse will continue on into the next yr .

Worst: They Didn’t Exactly Get On (S5 Ep1)

When season 5 began , no one would have thought that Mark and Lexie would have ended up together as it was decipherable that the two did n’t get along . Lexie hated the fashion he spoke to the intern and residents , and the way he ridicule George in front of their colleagues .

Mark did n’t exactly help himself either , as he was realise to bemock Lexie over her crush on George and separate her not to speak to him . Ideally , it was n’t an ideal start .

Best: Mark Believes In Lexie (S5 Ep3)

Up to this point , Mark and Lexie had only briefly interact , with the plastic sawbones teasing her over her crush on George . However , this was quite a pregnant milestonein this would - be romance as Mark was seen to be the only one to believe in Lexie ’s aesculapian expertness .

As many fans think , Lexie would often get ignored by Cristina and co. because she was only an intern . When Lexie figured out what was wrong with their patient role , everyone would dismiss her suggestion . Only Mark was willing to screen out her hypothesis and instruct . Fans did n’t comment it at the time but one would be able to see how happy Lexie was that Mark trust her instinct .

Worst: Mark Was Only Interested Because She Was “Forbidden Fruit” (S5 Ep9)

Mark and Lexie ’s human relationship was n’t precisely a cock-and-bull story love affair as the plastic sawbones ab initio had no interest in her . It was only until Derek warned him to stay away from her did his attractive feature towards Lexie start to farm .

Mark even admit to Derek that he did n’t even think of Lexie in that room until he put the thoughts in his head . If Lexie would have found out that he had only been interested in her because she was " off - terminal point , " it probably would n’t have lasted .

Best: Mark reveals the relationship to Derek (S5 Ep16)

Mark and Lexie were first assort as a forestall romance as the plastic operating surgeon was warn off by Derek . For calendar week , they kept their family relationship hidden from friends , meeting up at hotels and on - call room . However , the insistency of keeping it obliterate began to get to Lexie .

Lexie gave Mark an ultimatum : either he told Derek about them or they could n’t be together anymore . fan had seen how much he cared for Lexie , so it was n’t surprisingwhen Mark end up separate Derek . Although this moderate to another fall down out between the best ally , there was a courteous moment when Lexie came rushing to his aid .

Worst: Lexie’s stress eating (S5 Ep20)

Mark and Lexie ’s family relationship was still going unattackable weeks after the fight ; however , it begin to take its toll on Derek and Mark ’s friendly relationship , with the former still suffer by Mark ’s perfidy . It also took its toll on Lexie who find herself becharm in the middle of their arguments .

As a result , Lexie began to accentuate eat . Meredith then intervenes after noticing Markand Derek adjudicate to use Lexie to fire their work desires . Overall , it would n’t incisively make a person feel good if their partner is try on to use them for their own amplification .

Best: Mark Meets Lexie’s Dad (S5 Ep21)

Surprisingly , Mark continued to be the perfect boyfriend when he decided to meet Lexie ’s dad , Thatcher . Earlier in the episode , Mark was reluctant to meet Thatcher because he believe he would n’t care him . He also implied that he preferred their relationship to be secret and did n’t need an foreigner ’s position to deflower it . Lexie looked disappointed by his decision but respected it all the same .

However , Mark shortly deepen his nous after speaking with Callie . Something she said must have resonated with the charge plate attending as he sour up at the restaurant . Lexie looked taken aback but was nevertheless pleased that he bend up to fulfil her father . It showed her how attached Mark was to the relationship .

Worst: Lexie Doesn’t Want To Move In (S5 Ep23)

This was the installment where the viewers saw a tiny chap made in the relationship that eventually grew without any of the fans noticing . Even though Mark made a huge step in the family relationship by assemble Thatcher , it seem that he was willing to go even further to show his loyalty to Lexie by asking her to move in with him .

However , Lexie settle to pretend that she had no idea what he was allude to and showed excitement over him have " his own place . " Then , later on , Lexie intromit that she just was n’t quick for that . The signs that these two were heading towards different path were unmistakable but never properly picked up on .

Best: Lexie Moves In With Mark (S6 Ep2)

Although Lexie was quite adamant that she was n’t quite ready to move in with Mark , George ’s unexpected death and her bond with Clara help to change her mind . While Lexie had ab initio wanted to focus on her career , for the time being , she finally came to the ending that she was quick to move in with him .

Many fans loved this miniskirt - electric arc for Lexie as they were able-bodied to see the matureness between the couple spring up . Lexie took her metre with her conclusion and did n’t rush into it . In takings , Mark did n’t put any pressure on her and wanted her to decide when the fourth dimension was correct .

Worst: The Arrival Of Sloan (S6 Ep10)

As lover remember , Sloan ’s comportment end up being the reason why Mark and Lexie broke up . Not only did the young adult female drop the paternity bombshell in the eye of a oeuvre shift , but Mark immediately moved her into his and Lexie ’s apartment without even discussing it with her .

It was clear to all that Lexie was uncomfortable with the office . However , she , nevertheless , stayed quiet because she did n’t want to upset Mark . As everyone knows , this is n’t precisely how a healthy kinship should stretch .

Best: Attempting To Be A Family (S6 Ep10)

Although it was vindicated that Lexie was n’t exactly comfortable with their fresh keep situation , she still did her best to hear and make it work , while also helping to build the bail bond between father and daughter .

She talked to Sloan about his interests , gave her money to buy him a Christmas gift , and even gave Mark advice on how to talk to his daughter . While the pressure did eventually become too much for Lexie , she deserves a lot of credit for work the attachment between the two .

Side by side images of Lexie and Mark looking concerned and kissing on Grey’s Anatomy

TR Knight and Chyler Leigh

Lexie Grey and Cristina Yang sing Like A Virgin in Grey’s Anatomy

Lexie and Mark lying in a bed together in Grey’s Anatomy

Derek looking at Mark and Lexie in Grey’s Anatomy

Lexie Stress eating in Background

Mark behind Lexie in Grey’s Anatomy

Lexie at the attic in Meredith’s house

Lexie Grey holding her underwear and toothbrush in Grey’s Anatomy

Sloan holding her baby after giving birth in Grey’s Anatomy

Mark and Lexie sitting on the couch on Grey’s Anatomy

Grey’s Anatomy