The Big Bang Theory

The   Big Bang Theorymade a spattering with fans who could n’t get enough of the friendly relationship   between Sheldon , Leonard , Howard , and Raj . The inclusion of their wife and girlfriend in later season only added to the show ’s hilarity .

Throughout the halls of Caltech and the street of Pasadena , the A - list guest virtuoso that graced the show was also what madeTBBTexciting to watch . While some guest maven were famous before the show , others grew their fame years after appearing .

Updated on April 25th , 2022 , by Lynn Gibbs : Although The Big Bang Theory focalize on its core group group of characters , side fibre and guest whiz were add up throughout . From legendary names in the field of science to Star Trek actors , it was fun for TV audience to see which star they ’d have on next . Some guest stars appeared on the serial before they made the large - time , which made rewatching the serial all the more sport .

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Carrie Fisher As Herself

In the episode ‘ The Convention Conundrum , ’ Sheldon spend the nighttime withStar Warsactor James Earl Jones . The two break out to eat , run to a fair , and later played Ding Dong Ditch at Carrie Fisher ’s menage .

James and Sheldon surround her buzzer and then excitedly hunt aside when   she shew up at the door with a baseball game bat .   However , as soon as Fisher opened the door and James , she was in no laugh mood .   She screamed , “ It ’s not rummy James ! ” As he and Sheldon laughed while running away . Fisher ’s cameo was so minuscule that mostTBBTfans forgot she was in an instalment . Fisher passed away in 2016 but will forever be known for her function as Princess Leia in theStar Warsfranchise .

Jodi Lyn O’Keefe As Mikayla

Jodi Lyn O’Keefe is most known for her roles inPrison Break , The Vampire Diaries , andShe ’s All That . Instead of portraying herself like a few other stars on this list , O’Keefe played a Las Vegas prostitute diagnose Mikayla .

In the episode ‘ The Vegas Renormalization , ’ Leslie Winkle broke up with Howard and he was sad that he was alone yet again . After their schism , Howard got worse and worsebefore he got better . Since they were in Las Vegas , Leonard and Raj wanted to boost his sureness so they hired Mikayla to philander and catch some Z’s with Howard . know as “ the boyfriend experience , ” Howard did n’t realize she was a hired sexual activity proletarian until after their conversation , but he could n’t even be frantic at his friends because he   needed the company .

Rick Fox As Glenn

Rick Fox only star in one episode , ‘ The Love Car Displacement . ’ Fox is a former NBA - star turn actor who has been in shows likeOne Tree Hill , OZ , andMelrose Place .

In the episode , Fox play Bernadette ’s former professor and ex-husband - boyfriend Glenn . The two scarper into each other at a group discussion and Howard was directly intimidated by Glenn ’s stature and dear looks . Howard ’s response to Bernadette and Glenn once dating put him in boiling water and gaveBernadette some of her most savage consequence . At the end of the episode , Leonard felt what Howard was feeling when Glenn drive centime back to Las Angeles and was jealous something was going to happen between the two of them .

Jessica Walter As Mrs. Latham

In ‘ The Benefactor Factor , ” actress Jessica Walter played Mrs. Latham , a university giver concerned in Leonard ’s work .   Her involvement inLeonard ’s work made him seem the smartestin the radical , much to Sheldon ’s chagrin .

As an older , well-thought-of woman with a lot of money , Leonard and co. were intimidate by her power . But when Mrs. Latham take Leonard out to dinner to talk about his body of work , he felt like he had to for the safe of his life history . In a scandalous twist , Mrs. Latham flirted with Leonard and made it clear she want a amorous evening with him . The two ended up sleeping together and the following morning Leonard ’s department was given a donation . Walter sadly passed away in 2021 but will perpetually be known for her roles inArrested DevelopmentandArcher .

Howie Mandel As Himself

Howie Mandel is a TV personality known for authorship , act , and hosting . Due to his name , he appear in the episode where Howard ( or as Bernadette called him , Howie ) return home from space .

When Howard catch off the plane , there was a radical of paparazzo snapping his pic , calling out “ Howie ! ” Howard wave and thank them for come in but what he did n’t know was that Howie Mandel was right behind him . When Howard realized his welcoming was n’t as grand as he expected , he got upset that his friends were n’t there for support .

Danica McKellar As Abby

Danica McKellar is most known for starring inThe Wonder Years , but she ’s still acting today ,   appear in a ton of TV movies and shows .

OnTheBig Bang Theory , she appear in ' The Psychic Vortex . ' The installment had Sheldon join Raj as his wingman when he was tired of being solitary . Raj matured inThe Big Bang Theoryby putting himself out there in the date earthly concern instead of stay home out of fear . While many think this idea would blow up in smoke , it influence in Raj ’s favor . McKellar dally a charwoman named Abby who ended up fail home with Raj after hitting it off at the Browning automatic rifle . woefully , Abby never come back after that one episode .

Charlie Sheen As Himself

Actor Charlie Sheen   pop up up in ' The Griffin Equivalency ' during an important moment in Raj ’s life .

In the installment , Raj was choose as one of People Magazine ’s 30 under 30 people to see . The accomplishment went to his head and he started act other than around his friends . Leonard , Sheldon , and Howard could n’t stand to be around his pompous vigour , which led Raj to tell a random person at the bar that he was going to be in People Magazine . Sheen lento turn around and say , " Yeah , call me when you ’re on the top . "   This , of path , is about Sheen   being a tabloid power .

Eliza Dushku As Agent Angela Page

WhileHoward and Sheldon eventually rule commonground onTBBT , they were n’t always respectful of each other . In the installment ' The Apology Insufficiency , '   Howard had the chance to work for NASA but needed security measure headway .

Agent Angela Page visited Sheldon , Raj , and Leonard to make more perspective on the kind of person Howard was . But after Sheldon and the chemical group gave bad data , Angela never approve Howard ’s headway . Agent Page was played by actress Eliza Dushku .   Dushku is most eff as Missy inBring It On , but she ’s also been on the TV seriesHulk and the Agents of S.M.A.S.H. , Tru Calling , andBuffy the Vampire Slayer .

Judy Greer As Dr. Elizabeth Plimpton

Judy Greer has been in everything fromAnt - Man , 13 Going On 30 , and Modern Family — she was also in an sequence ofThe Big Bang Theory . Greer make for Dr. Elizabeth Plimpton in the episode ' The Plimpton Stimulation . '

As a   cosmological physicist , Plimpton stayed with Sheldon and Leonard when she was in townspeople for a group discussion . Leonard was star - struck when he met her because he take her book and followed her piece of work . Surprisingly , Leonard and Plimpton sleep together after coming together — shortly after violate up from Penny . Leonard wanted a family relationship with Plimpton but he soon learn that she also tried sleeping with Raj and Howard .

Octavia Spencer As The DMV Worker

Iconic actress Octavia Spencer appeared inTBBTas a invitee star in the instalment ' The Euclid Alternative . ' In the installment , the group of acquaintance were threadbare of ram Sheldon everywhere and forced him to get his permission .

At the DMV , Sheldon questioned Spencer ’s character about the test , which bother her because he was obligate up the line . Like most strangers who encountered Sheldon for the first sentence , she was confused and annoyed by him . Her time in the show was short but she ’s most bang for her   unbelievable film likeThe Help , Hidden figure , andThe Shack .

Summer Galu As Herself

In ' The Terminator Decoupling , ' Sheldon , Howard , Raj , and Leonard were on a train head to a conference when they sawFireflyactress Summer Glau . Everyone but Sheldon brainstormed how they would introduce themselves .

Eventually , Raj dare to make a move and the two shared a short conversation until Howard got ask . Howard thought of an inappropriate   pick - upline to make his mark on Summer but it did n’t act upon . Summer did n’t require anything to do with Howard and quickly got off the train after a few selfies with him . Summer did n’t have too many lines , but fan of hers recognize her fromGrey ’s Anatomy , Terminator : The Sarah Connor Chronicles , andArrow .

Judd Hirsch As Albert Hofstadter

Appearing in one episode in the 9th season as Dr. Alfred Hofstadter , actor Judd Hirsch starred as Leonard ’s successful dada . Although his dad is mentioned often throughout the season , viewers   never saw   him until Leonard and Penny ’s relationship timeline took them to their second marriage .

In this episode , viewers finally got to see Leonard ’s dad interact with his aggressive mother . Beverly Hofstadter ripped Albert ’s name to smidgin every chance she got when she was on covert , but in world , he was a loving and wizardly man .

Jerry O’Connell As George Cooper Jr.

Viewers never think they ’d meet Sheldon ’s older buddy George but it happened before his marriage to Amy . Sheldon ’s mom did n’t want him to get married without the financial support of his brother , so they were pull to make amends after a toxic relationship .

He first appeared in ' The Sibling Realignment ' and was later seen happily at the wedding party . Jerry O’Connell   is most know for his hit ' eighty movieStand by Mebut he ’s also been inSlidersandScream 2 .

George Takei As Himself

The amazing affair aboutThe Big Bang Theoryis that guest mavin from various shows and movies mentioned popped up from time to time . In one case , Star Trek’sGeorge Takei look in season 4 as an fanciful   shape in Howard ’s fantasy .

While Howard tried have a bedtime fantasy aboutBattlestar Galactica’sKatee Sackhoff , George Takei invaded the visual sensation   and gave Howard some dating advice . While Howard had a great lady friend in Bernadette , he always thought he ’d terminate up with someone " hot . " Now in his mid-80s , Takei still act and is most know for his fourth dimension inStar Trek , Mulan , andThe Duchess of Windsor .

NEXT:10 Girlfriends Of Leonard , Raj And Howard That We ’d All Love To Date

Three split images of guest stars on TBBT

Carrie Fisher holds a baseball bat to James Earl Jones and Sheldon on TBBT

Mikayla sitting at the bar in TBBT

A split image of Howard meeting Glenn for the first time on TBBT

Jessica Walter in The Big Bang Theory The Benefactor Factor

Howard and Howie Mandela arrive at the airport to fans on The Big Bang Theory

Danica McKellar As Abby talking to Sheldon on TBBT

Charlie Sheen sitting at a bar on TBBT

The Big Bang Theory - FBI Agent at Sheldon’s door

Dr. Elizabeth Plimpton talking to Leonard in the apartment on TBBT

Octavia Spencer As The DMV Worker in TBBT

Summer taking a selfie with Howard on TBBT

Leonard and his dad talking and smiling at home on TBBT

Georgie looking off camera on TBBT

George Takei talking to Howard in bed with two women on TBBT

The Big Bang Theory